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KMID : 1044320220240020035
Annals of Clinical Neurophysiology
2022 Volume.24 No. 2 p.35 ~ p.45
Diagnosis of complex regional pain syndrome
Kim Young-Do

Abstract
Complex regional pain syndrome (CRPS) is a chronic regional pain disorder that most frequently affects the limbs. It is characterized by hyperalgesia, allodynia, edema, motor disturbance, and vasomotor instability, and typically occurs following surgery or trauma. In type-I CRPS there is no confirmed nerve injury, while peripheral nerve injury is present in type-II CRPS. The multifactorial pathophysiological etiology of CRPS includes inflammation, autoimmune responses, abnormal cytokine production, autonomic dysfunction, altered blood flow, psychological factors, and central cortical reorganization. There are no specific laboratory diagnostic tools for CRPS, and so it is diagnosed clinically. The Budapest criteria are currently the most-accepted diagnostic criteria.
KEYWORD
Complex regional pain syndrome, Reflex sympathetic dystrophy, Causalgia
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